GLYAT Antibody
(Synonyms: ACGNAT; CAT; GAT)GLYAT Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to GLYAT.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P
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Reactivity :
Human, Mouse
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Formulation:
Spplied in pH 7.4 PBS, 0.05% NaN3, 40% Glycerol.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:50-200 |
Product Details
GLYAT Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to GLYAT.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse
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Calculated Molecular Weight Predicted band size: 18.3 kDa
Fusion protein of human GLYAT.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Spplied in pH 7.4 PBS, 0.05% NaN3, 40% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
GLYAT is a Mitochondrial acyltransferase which transfers an acyl group to the N-terminus of glycine and glutamine, although much less efficiently. Can conjugate numerous substrates to form a variety of N-acylglycines, with a preference for benzoyl-CoA over phenylacetyl-CoA as acyl donors. Thereby detoxify xenobiotics, such as benzoic acid or salicylic acid, and endogenous organic acids, such as isovaleric acid
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Subcellular Localization
Mitochondrion
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Expression
Tissue_Specificity: Predominantly expressed in liver (at protein level) and kidney. Down-regulated in hepatocellular carcinoma and other liver cancers. -
Isoforms & Post-Translational Modification
GLYAT has 2 isoforms, Q6IB77-1: amino acid length is 296, molecular weight is 33924 Da (predicted); Q6IB77-2: amino acid length is 163, molecular weight is 18506 Da (predicted).
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SwissProt ID
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Synonyms
ACGNAT; CAT; GAT
Documentation
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