GPR17 Antibody (YA8046)
(Synonyms: DKFZp686M18273)GPR17 Antibody (YA8046) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GPR17.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-150 |
Product Details
GPR17 Antibody (YA8046) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GPR17.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
Synthetic peptide within Human GPR17 C-terminal. The exact sequence is proprietary.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
GPR17 dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia
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Subcellular Localization
Cell membrane
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Expression
Tissue_Specificity: Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain -
Isoforms & Post-Translational Modification
Q13304 has two isomers: Q13304-1: 40989 Da (predicted); Q13304-2: 37827 Da (predicted).
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SwissProt ID
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Synonyms
DKFZp686M18273
Documentation