ING1 Antibody (YA3018)
(Synonyms: p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a)ING1 Antibody (YA3018) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ING1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-1:1000 |
Product Details
ING1 Antibody (YA3018) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ING1.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 47 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 47 kDa
Entrez Gene: 3621 Human ; 26356 Mouse ; 306626 Rat
SwissProt: Q9UK53 Human ; Q9QXV3 Mouse ;
OMIM: 275355 Human
A synthetic peptide of human ING1
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ING1 is a Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene
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Subcellular Localization
Nucleus
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Expression
Tissue_specificity:Isoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines -
Isoforms & Post-Translational Modification
Q9UK53 has 5 isomers: Q9UK53-1: 46738 Da (predicted); Q9UK53-2: 31864 Da (predicted); Q9UK53-3: 23671 Da (predicted); Q9UK53-4: 26757 Da (predicted); Q9UK53-5: 29572 Da (predicted).
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Subunit
Interacts with H3K4me3 and to a lesser extent with H3K4me2. Interacts with TP53. Isoform 2 interacts with RSL1D1
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SwissProt ID
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Synonyms
p33; p47; p33ING1; p24ING1c; p33ING1b; p47ING1a
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Research Field
Cell Biology
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