KIF3A Antibody (YA3366)
(Synonyms: KIF 3; KIF 3A; Kifl; Kinesin family member 3A; Kinesin like protein KIF 3A; Kinesin-like protein KIF3A; Kns3)KIF3A Antibody (YA3366) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KIF3A.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IP
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IP
IP: Immunoprecipitation
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|---|---|---|
| Dilution Ratio | 1:1000-1:2000 | 1:50 |
Product Details
KIF3A Antibody (YA3366) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KIF3A.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 80 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 80 kDa
Entrez Gene: 11127 Human ; 16568 Mouse ; 84392 Rat
SwissProt: Q9Y496 Human ; P28741 Mouse ;
OMIM: 604683 Human
A synthesized peptide derived from human KIF3A aa640-699/699.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KIF3A is a Microtubule-based anterograde translocator for membranous organelles. Plus end-directed microtubule sliding activity in vitro. Plays a role in primary cilia formation. Plays a role in centriole cohesion and subdistal appendage organization and function. Regulates the formation of the subdistal appendage via recruitment of DCTN1 to the centriole. Also required for ciliary basal feet formation and microtubule anchoring to mother centriole
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Subcellular Localization
Cytoplasm, cytoskeleton; Cell projection, cilium; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole
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Subunit
Heterodimer of KIF3A and KIF3B (By similarity). Interacts with CIMAP3 (PubMed:20643351). Interacts with CLN3 (PubMed:22261744).
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SwissProt ID
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Synonyms
KIF 3; KIF 3A; Kifl; Kinesin family member 3A; Kinesin like protein KIF 3A; Kinesin-like protein KIF3A; Kns3
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Research Field
Signal Transduction
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