Lipoprotein Lipase Antibody (YA4954)
(Synonyms: LPL; LIPD; Lipoprotein lipase; LPL)Lipoprotein Lipase Antibody (YA4954) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Lipoprotein Lipase.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB; IHC-P; IHC-F; IF-Tissue
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Reactivity :
Human
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Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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|---|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:100-200 | 1:100-200 |
Product Details
Lipoprotein Lipase Antibody (YA4954) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to Lipoprotein Lipase.
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Host Rabbit
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Clonality Monoclonal,Recombinant
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 53 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 53 kDa
A synthesized peptide derived from human Lipoprotein lipase. The exact sequence is proprietary to MCE.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Lipoprotein Lipase is key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Although it has both phospholipase and triglyceride lipase activities it is primarily a triglyceride lipase with low but detectable phospholipase activity. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans[1][2][3][4][5][6][7].
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Subcellular Localization
Cell membrane; Peripheral membrane protein; Extracellular side; Secreted; Secreted, extracellular space, extracellular matrix
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Expression
Tissue_specificity:Detected in plasma (PubMed:11893776, PubMed:12641539, PubMed:2340307) . Detected in milk (protein level) (PubMed:2340307) . -
Subunit
Homodimer (Probable) (PubMed:11893776, PubMed:16179346, PubMed:26725083). Interacts with GPIHBP1 with 1:1 stoichiometry (PubMed:17997385, PubMed:26725083, PubMed:27811232, PubMed:27929370, PubMed:29899144, PubMed:30559189).
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SwissProt ID
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Synonyms
LPL; LIPD; Lipoprotein lipase; LPL
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