MAGEA1 Antibody (YA1105)
(Synonyms: MAGEA1; MAGE1, MAGE1A; Melanoma-associated antigen 1; Antigen MZ2-E; Cancer/testis antigen 1.1 (CT1.1); MAGE-1 antigen)MAGEA1 Antibody (YA1105) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAGEA1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.265.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:100-1:200 |
Product Details
MAGEA1 Antibody (YA1105) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MAGEA1.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 45 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 34 kDa
A synthesized peptide derived from human MAGEA1
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.265.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MAGEA1 may be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes
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Subcellular Localization
Cytoplasm; Nucleus
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Expression
Tissue_specificity:This gene is expressed in various types of tumors, such as melanoma, head and neck squamous cell carcinoma, lung cancer, and breast cancer, but not in normal tissues other than the testes. It has never been expressed in kidney tumors, leukemia, or lymphoma. -
Subunit
Interacts with SNW1 and HDCA1
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SwissProt ID
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Synonyms
MAGEA1; MAGE1, MAGE1A; Melanoma-associated antigen 1; Antigen MZ2-E; Cancer/testis antigen 1.1 (CT1.1); MAGE-1 antigen
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Research Field
Tags & Cell Markers
Documentation
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