2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies
  5. MCF2 Antibody (YA8841)

MCF2 Antibody (YA8841) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MCF2.

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容量 在庫状況
50 μL   お問い合わせ  
100 μL   お問い合わせ  

* アイテムを追加する前、数量をご選択ください

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 説明

製品説明

MCF2 Antibody (YA8841) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to MCF2.
Host

Mouse
Clonality

Monoclonal
Species Reactivity
Human
SwissProt ID
Immunogen

Human recombinant protein fragment corresponding to amino acids 872-1001 of human MCF2 produced in E.coli.
Application &
Dilution Ratio
Application Dilution Ratio
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:500-800
Sensitivity Endogenous 純度 Affinity purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG1  
Appearance

Liquid
Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
輸送条件

Shipping with blue ice.
Background
Function：Guanine nucleotide exchange factor (GEF) that modulates the Rho family of GTPases. Promotes the conversion of some member of the Rho family GTPase from the GDP-bound to the GTP-bound form. Isoform 1 exhibits no activity toward RHOA, RAC1 or CDC42. Isoform 2 exhibits decreased GEF activity toward CDC42. Isoform 3 exhibits a weak but significant activity toward RAC1 and CDC42. Isoform 4 exhibits significant activity toward RHOA and CDC42. The truncated DBL oncogene is active toward RHOA, RAC1 and CDC42
Subcellular Localization：Cytoplasm,Membrane,Membrane
Expression：
Tissue_Specificity: Isoform 1 is expressed only in brain. Isoform 3 is expressed in heart, kidney, spleen, liver and testis. Isoform 4 is expressed in brain, heart, kidney, testis, placenta, stomach and peripheral blood. The protein is detectable in brain, heart, kidney, intestine, muscle, lung and testis
Isoforms & Post-Translational Modification：P10911 has 6 isomers: P10911-1: 107673 Da (predicted); P10911-2: 100409 Da (predicted); P10911-3: 114376 Da (predicted); P10911-4: 109436 Da (predicted); P10911-5: 116139 Da (predicted); P10911-6: 95940 Da (predicted).
Phosphorylation by TNK2 enhances guanine nucleotide exchange factor (GEF) activity toward Rho family proteins
Subunit：Interacts with an array of inositol phospholipids such as phosphatidylinositol 3-phosphate (PI3P), phosphatidylinositol 4-phosphate (PI4P) and phosphatidylinositol 5-phosphate (PI5P)
Synonyms
ARHGEF21; DBL
ドキュメンテーション
User Guide for Antibodies (1077 KB)

MCF2 Antibody (YA8841) 関連分類

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
MCF2 Antibody (YA8841)
製品番号:
HY-P89157
数量:
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