PNLDC1 Antibody (YA7066)
(Synonyms: PNDC1_HUMAN antibody; PNLDC1 antibody; poly(A)-specific ribonuclease (PARN)-like domain containing 1 antibody; Poly(A)-specific ribonuclease PARN-like domain-containing protein 1 antibody; RP1-195P10.1 antibody)PNLDC1 Antibody (YA7066) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PNLDC1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:2000 |
Product Details
PNLDC1 Antibody (YA7066) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PNLDC1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 60 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 60 kDa
Recombinant protein within human PNLDC1 aa 101-250.
Endogenous
Protein A affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PNLDC1 is a 3'-exoribonuclease that has a preference for poly(A) tails of mRNAs, thereby efficiently degrading poly(A) tails. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs and is also used to silence certain maternal mRNAs translationally during oocyte maturation and early embryonic development. May act as a regulator of multipotency in embryonic stem cells. Is a critical factor for proper spermatogenesis, involved in pre-piRNAs processing to generate mature piRNAs[1][2].
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Subcellular Localization
Endoplasmic reticulum membrane
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Isoforms & Post-Translational Modification
Q8NA58 has two isomers: Q8NA58-1: 60124 Da (predicted); Q8NA58-2: 61311 Da (predicted).
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SwissProt ID
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Synonyms
PNDC1_HUMAN antibody; PNLDC1 antibody; poly(A)-specific ribonuclease (PARN)-like domain containing 1 antibody; Poly(A)-specific ribonuclease PARN-like domain-containing protein 1 antibody; RP1-195P10.1 antibody
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