PRRT2 Antibody (YA8050)
(Synonyms: BFIC2; BFIS2; DSPB3; DYT10; EKD1; FICCA; ICCA; IFITMD1; PKC)PRRT2 Antibody (YA8050) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRRT2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:2000-2500 |
Product Details
PRRT2 Antibody (YA8050) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PRRT2.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
Human recombinant protein fragment corresponding to amino acids 152-268 of human PRRT2 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PRRT2 is an As a component of the outer core of AMPAR complex, may be involved in synaptic transmission in the central nervous system. In hippocampal neurons, in presynaptic terminals, plays an important role in the final steps of neurotransmitter release, possibly by regulating Ca(2+)-sensing. In the cerebellum, may inhibit SNARE complex formation and down-regulate short-term facilitation
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Subcellular Localization
Cell membrane,Presynaptic cell membrane,Synapse,Cell projection, axon,Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane,Postsynaptic density membrane,Cell projection, dendritic spine
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Isoforms & Post-Translational Modification
Q7Z6L0 has three isomers: Q7Z6L0-1: 34945 Da (predicted); Q7Z6L0-2: 40228 Da (predicted); Q7Z6L0-3: 30653 Da (predicted).
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Subunit
Component of the outer core of AMPAR complex (PubMed:25915028)
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SwissProt ID
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Synonyms
BFIC2; BFIS2; DSPB3; DYT10; EKD1; FICCA; ICCA; IFITMD1; PKC
Documentation
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