2. Antibodies
  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. SERCA1 ATPase Antibody (YA2157)

SERCA1 ATPase Antibody (YA2157)

Cat. No.: HY-P82412
User Guide for Antibodies Technical Support

SERCA1 ATPase Antibody (YA2157) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SERCA1 ATPase.

For research use only. We do not sell to patients.

Size Price Stock Quantity
20 μL Get quote 4 - 5 Weeks 3 - 4 Weeks 5 - 6 Weeks 4 - 5 weeks
50 μL Get quote 4 - 5 Weeks 3 - 4 Weeks 5 - 6 Weeks 4 - 5 weeks
100 μL Get quote 4 - 5 Weeks 3 - 4 Weeks 5 - 6 Weeks 4 - 5 weeks
250 μL   Get quote  
Synthetic products have potential research and development risk.
or Bulk Inquiry

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

SERCA1 ATPase Antibody (YA2157) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SERCA1 ATPase.
Host

Rabbit
Clonality

Recombinant,Monoclonal
Molecular Weight
Predicted band size: 110 kDa;
Observed band size: 100 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthesized peptide derived from human ATP2A1/SERCA1 aa1-54/1001.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:1000-1:2000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:100-1:200
IP
IP: Immunoprecipitation
1:50
Sensitivity Endogenous Purity Affinity Chromatography
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen (By similarity). Contributes to calcium sequestration involved in muscular excitation/contraction (PubMed:10914677)
Subcellular Localization：Endoplasmic reticulum membrane; Multi-pass membrane protein; Sarcoplasmic reticulum membrane; Multi-pass membrane protein
Expression：
Tissue_specificity:Skeletal muscle, fast-twitch fibers (Type II)

Induction:Increased contractile activity leads to a decrease in SERCA1 expression, while decreased contractile activity leads to an increase in SERCA1 expression
Isoforms & Post-Translational Modification：O14983 has 3 isomers: O14983-1: 110252 Da (predicted); O14983-2: 109283 Da (predicted); O14983-3: 95199 Da (predicted).
Subunit：Interacts with sarcolipin (SLN) (By similarity). Interacts with phospholamban (PLN) (By similarity). Interacts with myoregulin (MRLN). Interacts with DWORF (By similarity). Interacts with VMP1 (PubMed:28890335)
Database

Entrez Gene: 487 Human

SwissProt: O14983 Human

OMIM: 601003 Human

Research Field

Tags & Cell Markers
Synonyms
ATP2A; ATP2A1; SERCA1
Documentation
User Guide for Antibodies (1077 KB)

SERCA1 ATPase Antibody (YA2157) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Requested Quantity *

Applicant Name *

 

Salutation

Email Address *

 

Phone Number *

Department

 

Organization Name *

City

State

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
SERCA1 ATPase Antibody (YA2157)
Cat. No.:
HY-P82412
Quantity:
MCE Japan Authorized Agent:

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Country or Region *

Email Address *

     

Phone Number *

 

Organization Name *

Remarks

SAFETY DATA SHEET (SDS)

Request for HNMR Report

We have received your request and will respond to you as soon as possible.