SerpinB3 Antibody (YA6905)
(Synonyms: HsT1196 antibody)
Based on 1 Customer Validation
SerpinB3 Antibody (YA6905) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to SerpinB3.
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Host:
Mouse
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Isotype:
IgG
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Application:
IHC-P, IHC-F, IF-Tissue
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Reactivity :
Human
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Formulation:
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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|---|---|---|---|
| Dilution Ratio | 1:100-500 | 1:100-500 | 1:100-500 |
Product Details
SerpinB3 Antibody (YA6905) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to SerpinB3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 46kDa
Recombinant human SERPINB3 protein. The exact sequence is proprietary to MCE.
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SerpinB3 may act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1)
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Subcellular Localization
Cytoplasm
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Expression
Tissue_Specificity: Squamous cells. Expressed in some hepatocellular carcinoma (at protein level)
Induction: Strongly up-regulated in the upper epidermis of sun-exposed skin -
Isoforms & Post-Translational Modification
P29508 has two isomers: P29508-1: 44565 Da (predicted); P29508-2: 38550 Da (predicted).
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Subunit
Interacts with MAPK8/JNK1
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SwissProt ID
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Synonyms
HsT1196 antibody
Documentation
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