SHANK2 Antibody (YA7016)
(Synonyms: AUTS17 antibody; Cortactin binding protein 1 antibody; Cortactin SH3 domain-binding protein antibody; Cortactin-binding protein 1 antibody; CortBP1 antibody; CTTNBP1 antibody; GKAP/SAPAP interacting protein antibody; GKAP/SAPAP-interacting protein antibody; KIAA1022 antibody; Proline rich synapse associated protein 1 antibody)SHANK2 Antibody (YA7016) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SHANK2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IF-Tissue
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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|---|---|---|---|
| Dilution Ratio | 1:2000 | 1:50-1:100 | 1:200 |
Product Details
SHANK2 Antibody (YA7016) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SHANK2.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 159 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 201 kDa
Recombinant protein within human SHANK2 aa 901-1,230.
Endogenous
Protein A affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
SHANK2 is a Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction
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Subcellular Localization
Apical cell membrane,Cytoplasm,Synapse,Postsynaptic density,Cell projection, growth cone,Cell projection, dendritic spine
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Expression
Tissue_Specificity: Isoform 3 is present in epithelial colonic cells (at protein level) -
Isoforms & Post-Translational Modification
Q9UPX8 has four isomers: Q9UPX8-3: 201261 Da (predicted); Q9UPX8-1: 158822 Da (predicted); Q9UPX8-2: 30564 Da (predicted); Q9UPX8-4: 134931 Da (predicted).
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Subunit
Is part of a complex with DLG4/PSD-95 and DLGAP1/GKAP
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SwissProt ID
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Synonyms
AUTS17 antibody; Cortactin binding protein 1 antibody; Cortactin SH3 domain-binding protein antibody; Cortactin-binding protein 1 antibody; CortBP1 antibody; CTTNBP1 antibody; GKAP/SAPAP interacting protein antibody; GKAP/SAPAP-interacting protein antibody; KIAA1022 antibody; Proline rich synapse associated protein 1 antibody
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