SHANK2 Antibody (YA7016)

Cat. No.: HY-P87333: Data Sheet User Guide for Antibodies
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SHANK2 Antibody (YA7016) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SHANK2.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

SHANK2 Antibody (YA7016) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SHANK2.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 201 kDa;

Observed band size: 159 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9UPX8

Immunogen

Recombinant protein within human SHANK2 aa 901-1,230.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:200

Sensitivity	Endogenous	Purity	Protein A affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction

Subcellular Localization：Apical cell membrane,Cytoplasm,Synapse,Postsynaptic density,Cell projection, growth cone,Cell projection, dendritic spine

Expression：
Tissue_Specificity: Isoform 3 is present in epithelial colonic cells (at protein level)

Isoforms & Post-Translational Modification：Q9UPX8 has four isomers: Q9UPX8-3: 201261 Da (predicted); Q9UPX8-1: 158822 Da (predicted); Q9UPX8-2: 30564 Da (predicted); Q9UPX8-4: 134931 Da (predicted).

Subunit：Is part of a complex with DLG4/PSD-95 and DLGAP1/GKAP

Synonyms

AUTS17 antibody; Cortactin binding protein 1 antibody; Cortactin SH3 domain-binding protein antibody; Cortactin-binding protein 1 antibody; CortBP1 antibody; CTTNBP1 antibody; GKAP/SAPAP interacting protein antibody; GKAP/SAPAP-interacting protein antibody; KIAA1022 antibody; Proline rich synapse associated protein 1 antibody

Documentation

User Guide for Antibodies (1077 KB)