TBR1 Antibody (YA6793)
(Synonyms: T box brain 1 antibody; T box brain protein 1 antibody; T brain 1 protein antibody; T-box brain protein 1 antibody; T-brain-1 antibody; TBR 1 antibody; TBR-1 antibody; Tbr1 antibody; TBR1_HUMAN antibody; TES 56 antibody; T box brain 1 antibody; T box brain protein 1 antibody; T brain 1 protein antibody; T-box brain protein 1 antibody; T-brain-1 antibody; TBR 1 antibody; TBR-1 antibody; Tbr1 antibody; TBR1_HUMAN antibody; TES 56 antibody; TES-56 antibody; )TBR1 Antibody (YA6793) is a Rat -derived and non-conjugated IgG monoclonal antibody, targeting to TBR1.
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Host:
Rat
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Isotype:
IgG
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Application:
IHC-F, IHC-P, WB
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Reactivity :
Mouse, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-F
IHC-F: Immunohistochemistry-Frozen
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|---|
| Dilution Ratio | 1:500 | 1:1000 WB: 1:2000 |
Product Details
TBR1 Antibody (YA6793) is a Rat -derived and non-conjugated IgG monoclonal antibody, targeting to TBR1.
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Host Rat
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Clonality Recombinant,Monoclonal
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Species ReactivityMouse, Rat Predicted Reactivity: Cynomolgus monkey,Pig
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 74 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 74 kDa
Synthetic peptide within Human TBR1 aa 30-75 / 682.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TBR1 transcriptional repressor involved in multiple aspects of cortical development, including neuronal migration, laminar and areal identity, and axonal projection. As transcriptional repressor of FEZF2, it blocks the formation of the corticospinal (CS) tract from layer 6 projection neurons, thereby restricting the origin of CS axons specifically to layer 5 neurons[1][2].
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Subcellular Localization
Nucleus
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Expression
Tissue_Specificity: Brain -
Isoforms & Post-Translational Modification
Q16650 has two isomers: Q16650-1: 74053 Da (predicted); Q16650-2: 42332 Da (predicted).
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Subunit
Homodimer (PubMed:25232744)
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SwissProt ID
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Synonyms
T box brain 1 antibody; T box brain protein 1 antibody; T brain 1 protein antibody; T-box brain protein 1 antibody; T-brain-1 antibody; TBR 1 antibody; TBR-1 antibody; Tbr1 antibody; TBR1_HUMAN antibody; TES 56 antibody; T box brain 1 antibody; T box brain protein 1 antibody; T brain 1 protein antibody; T-box brain protein 1 antibody; T-brain-1 antibody; TBR 1 antibody; TBR-1 antibody; Tbr1 antibody; TBR1_HUMAN antibody; TES 56 antibody; TES-56 antibody;
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