TN-X Antibody (YA1237)(PBS only)

Cat. No.: HY-P81492A: Data Sheet User Guide for Antibodies
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TN-X Antibody (YA1237) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TN-X.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

TN-X Antibody (YA1237) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to TN-X.

Host

Rabbit

Molecular Weight

Predicted band size: 458 kDa;

Observed band size: 75/140 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P22105

Gene ID

7148 [NCBI]

Immunogen

A synthesized peptide derived from human TNXB

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors

Subcellular Localization：Secreted, extracellular space, extracellular matrix

Expression：
Tissue_specificity:Highly expressed in fetal adrenal, in fetal testis, fetal smooth, striated and cardiac muscle. Isoform XB-short is only expressed in the adrenal gland

Isoforms & Post-Translational Modification：P22105 has 4 isomers: P22105-3: 458388 Da (predicted); P22105-1: 458220 Da (predicted); P22105-2: 74030 Da (predicted); P22105-4: 458535 Da (predicted).

Subunit：Homotrimer. Interacts with type I, III and V collagens and tropoelastin via its 29th fibronectin type-III domain

Research Field

Signal Transduction

Synonyms

Tenascin X; TNXB; XB; TNX; XBS; HXBL; TENX; TN-X; TNXB1; TNXB2; Tenascin-X

Documentation

User Guide for Antibodies (1077 KB)