TSN Antibody (YA8764)
(Synonyms: BCLF-1; C3PO; RCHF1; REHF-1; TBRBP; TRSLN)TSN Antibody (YA8764) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TSN.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:500-800 |
Product Details
TSN Antibody (YA8764) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to TSN.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 26 kDa
Human recombinant protein fragment corresponding to amino acids 1-51 of human TSN produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TSN is a DNA-binding protein that specifically recognizes consensus sequences at the breakpoint junctions in chromosomal translocations, mostly involving immunoglobulin (Ig)/T-cell receptor gene segments. Seems to recognize single-stranded DNA ends generated by staggered breaks occurring at recombination hot spots|Exhibits both single-stranded and double-stranded endoribonuclease activity. May act as an activator of RNA-induced silencing complex (RISC) by facilitating endonucleolytic cleavage of the siRNA passenger strand
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Subcellular Localization
Cytoplasm,Nucleus
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Isoforms & Post-Translational Modification
Q15631 has two isomers: Q15631-1: 26183 Da (predicted); Q15631-2: 17279 Da (predicted).
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Subunit
Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring
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SwissProt ID
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Synonyms
BCLF-1; C3PO; RCHF1; REHF-1; TBRBP; TRSLN
Documentation
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