ZBTB4 Antibody (YA8037)
(Synonyms: KAISO-L1; ZNF903)ZBTB4 Antibody (YA8037) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ZBTB4.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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|---|---|
| Dilution Ratio | 1:500-800 |
Product Details
ZBTB4 Antibody (YA8037) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ZBTB4.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
Human recombinant protein fragment corresponding to amino acids 788-1013 of human ZBTB4 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ZBTB4 transcriptional repressor with bimodal DNA-binding specificity. Represses transcription in a methyl-CpG-dependent manner. Binds with a higher affinity to methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' but can also bind to the non-methylated consensus sequence 5'-CTGCNA-3' also known as the consensus kaiso binding site (KBS). Can also bind specifically to a single methyl-CpG pair and can bind hemimethylated DNA but with a lower affinity compared to methylated DNA. Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal[1].
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Subcellular Localization
Nucleus,Chromosome
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Isoforms & Post-Translational Modification
Q9P1Z0: 1013 amino acids, molecular weight 105114 Da.
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Subunit
Interacts with HIPK2
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SwissProt ID
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Synonyms
KAISO-L1; ZNF903
Documentation
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