1. Saccharides and Glycosides
    Terpenoids and Glycosides
  2. Atractyloside potassium salt

Atractyloside potassium salt 

Cat. No.: HY-N1462 Purity: 99.93%
Handling Instructions

Atractyloside potassium salt is a toxic diterpenoid glycoside isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart.

For research use only. We do not sell to patients.

Atractyloside potassium salt Chemical Structure

Atractyloside potassium salt Chemical Structure

CAS No. : 102130-43-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 574 In-stock
Estimated Time of Arrival: December 31
500 μg USD 70 In-stock
Estimated Time of Arrival: December 31
1 mg USD 110 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 650 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

Atractyloside potassium salt is a toxic diterpenoid glycoside isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart[1][2][3].

Molecular Weight

802.99

Formula

C₃₀H₄₄K₂O₁₆S₂

CAS No.

102130-43-8

SMILES

[H][[email protected]@]12C(C(O)=O)C[[email protected]@H](O[[email protected]]3[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]@H](CO)O3)OS(=O)([O-])=O)OS(=O)([O-])=O)OC(CC(C)C)=O)C[[email protected]@]1(C)[[email protected]@]4([H])[[email protected]@]5([[email protected]@H](O)C([[email protected]](CC4)C5)=C)CC2.[K+].[K+]

Shipping

Room temperature in continental US; may vary elsewhere

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (311.34 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2453 mL 6.2267 mL 12.4535 mL
5 mM 0.2491 mL 1.2453 mL 2.4907 mL
10 mM 0.1245 mL 0.6227 mL 1.2453 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (2.59 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (2.59 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (2.59 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Product Name:
Atractyloside potassium salt
Cat. No.:
HY-N1462
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