(Rac)-AZD8186
Rac)-AZD8186 is the racemate of AZD8186 (HY-12330), a PI3K inhibitor that inhibits PI3Kβ (IC50=4 nM), PI3Kδ (IC50=12 nM), PI3Kα (IC50=35 nM) and PI3Kγ (IC50=675 nM).
For research use only. We do not sell to patients.
- CAS No.: 1296270-45-5
- Formula: C24H25F2N3O4
- Molecular Weight:457.47
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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PI3Kα 35 nM (IC50) |
PI3Kβ 4 nM (IC50) |
PI3Kδ 12 (IC50) |
PI3Kγ 675 (IC50) |
Chemical Information
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CAS No. 1296270-45-5
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Molecular Weight 457.47
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Formula C24H25F2N3O4
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SMILES
O=C(C1=CC(C(NC2=CC(F)=CC(F)=C2)C)=C3C(C(C=C(N4CCOCC4)O3)=O)=C1)N(C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(Rac)-AZD8186 Related Classifications
HY-108958 Related Classifications
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