1296270-45-5
1296270-45-5
Chemical Structure
(Rac)-AZD8186
- CAS No.: 1296270-45-5
- Formula:C24H25F2N3O4
- Molecular Weight:457.47
IUPAC Name: 8-(1-((3,5-difluorophenyl)amino)ethyl)-N,N-dimethyl-2-morpholino-4-oxo-4H-chromene-6-carboxamide
InChIKey: LMJFJIDLEAWOQJ-UHFFFAOYSA-N
SMILES: O=C(C1=CC(C(NC2=CC(F)=CC(F)=C2)C)=C3C(C(C=C(N4CCOCC4)O3)=O)=C1)N(C)C
Biological Activity: Rac)-AZD8186 is the racemate of AZD8186 (HY-12330), a PI3K inhibitor that inhibits PI3Kβ (IC50=4 nM), PI3Kδ (IC50=12 nM), PI3Kα (IC50=35 nM) and PI3Kγ (IC50=675 nM)[1].
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(Rac)-AZD8186 | Rac)-AZD8186 is the racemate of AZD8186 (HY-12330), a PI3K inhibitor that inhibits PI3Kβ (IC50=4 nM), PI3Kδ (IC50=12 nM), PI3Kα (IC50=35 nM) and PI3Kγ (IC50=675 nM). | |||||||||||||||||||||
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References
Keywords
