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Cat. No.: HY-404047

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GS-1427 intermediate-2

GS-1427 intermediate-2 is a key intermediate in the synthesis of GS-1427 (HY-175745).

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CAS No.: 2417310-64-4
Formule: C₄₀H₃₃N₅O₄
Masse moléculaire:647.72

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

GS-1427 intermediate-2 Chemical Structure

CAS No.: 2417310-64-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

GS-1427 intermediate-2 is a key intermediate in the synthesis of GS-1427 (HY-175745)^[1].

Chemical Information

CAS No. 2417310-64-4
Masse moléculaire 647.72
Formule C₄₀H₃₃N₅O₄
SMILES

O=C(C1=CC=NC=C1N(C2=O)C)N2C3=CC=C(C4=C3N=CC=C4)C[C@@H](C(OC)=O)NC(C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Leena Patel, et al. Discovery of GS-1427: A potent and selective, oral α4β7 inhibitor for the treatment of inflammatory bowel disease. ACS. 2025 Aug 20.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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