NNRT-IN-14
NNRT-IN-14 is an HIV-1 reverse transcriptase inhibitor (IC50 = 0.175 µM). NNRT-IN-14 can form hydrogen bonds with LYS101, PRO225, and PHE227, and π–π stacking with TYR181 and TRP229. NNRT-IN-14 can be used for the study of HIV.
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- Formule: C25H18N6O
- Masse moléculaire:418.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
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HIV-1 0.175 μM (IC50) |
NNRT-IN-14 (Compound 19a) (1 μM, 1 h) shows an inhibition rate of 84.86% against HIV-1 RT, with an IC50 value of 0.175 μM[1].
NNRT-IN-14 (50 μg/mL, 48 h) shows no significant toxicity to either cancer cells or normal cells (IC50 > 119.5 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 418.45
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Formule C25H18N6O
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SMILES
CC1=C(OC2=C(C=NC=C3)C3=NC(NC4=CC=C(C#N)C=N4)=C2)C(C)=CC(/C=C/C#N)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NNRT-IN-14 Related Classifications
HY-178923 Related Classifications
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