1001341-27-0
Chemical Structure
TG 100948
- CAS No.: 1001341-27-0
- Formula:C31H28ClF3N6O3
- Molecular Weight:625.05
IUPAC Name: 2-chloro-N-(2-((4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)amino)pyrimidin-5-yl)-5-(3-(trifluoromethyl)benzamido)benzamide
InChIKey: FKDXTKROKGYHBQ-UHFFFAOYSA-N
SMILES: O=C(NC1=CC=C(Cl)C(=C1)C(=O)NC2=CN=C(N=C2)NC3=CC=C(OCCN4CCCC4)C=C3)C5=CC=CC(=C5)C(F)(F)F
Biological Activity: TG 100948 is a dual VEGFR and tyrosine kinase Src inhibitor. TG 100948 reduces retinal edema and retinal thickening, and eliminates bullous edema cysts in a rat model of ischemic retinal vein occlusion. TG 100948 can be used for the research of ischemic retinal vein occlusion[1].
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TG 100948 | TG 100948 is a dual VEGFR and tyrosine kinase Src inhibitor. TG 100948 reduces retinal edema and retinal thickening, and eliminates bullous edema cysts in a rat model of ischemic retinal vein occlusion. TG 100948 can be used for the research of ischemic retinal vein occlusion. | |||||||||||||||||||||
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Keywords
