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Cat. No.: HY-W423707

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TG 100948

TG 100948 is a dual VEGFR and tyrosine kinase Src inhibitor. TG 100948 reduces retinal edema and retinal thickening, and eliminates bullous edema cysts in a rat model of ischemic retinal vein occlusion. TG 100948 can be used for the research of ischemic retinal vein occlusion.

For research use only. We do not sell to patients.

CAS No.: 1001341-27-0
Formula: C₃₁H₂₈ClF₃N₆O₃
Molecular Weight:625.05

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

TG 100948 Chemical Structure

CAS No.: 1001341-27-0

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Sample (0.1mg)

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(In Japan)

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All VEGFR Isoforms :

Chemical Information

CAS No. 1001341-27-0
Molecular Weight 625.05
Formula C₃₁H₂₈ClF₃N₆O₃
SMILES

O=C(NC1=CC=C(Cl)C(=C1)C(=O)NC2=CN=C(N=C2)NC3=CC=C(OCCN4CCCC4)C=C3)C5=CC=CC(=C5)C(F)(F)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. S. P. Mahesh, et al. Topical Dual VEGF Receptor/Src Kinase
Inhibition as Potential Therapies for Retinal Edema Associated With Ischemic Retinal Vascular Disorders. Investigative Ophthalmology & Visual Science May 2008, Vol.49, 6114.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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