1011528-67-8
1011528-67-8
Chemical Structure
Phanginin J
- CAS No.: 1011528-67-8
- Formula:C21H26O5
- Molecular Weight:358.43
InChIKey: LJLAEZBPAANDEF-UJYBSYEXSA-N
SMILES: O=C[C@@]12[C@](CC[C@]3([H])[C@]2([H])CC4=C(C=CO4)[C@@H]3C)([H])[C@@](C=O)(CCC1)C(OC)=O
Biological Activity: Phanginin J is a Cassane-type furanoditerpene found in the seeds of Caesalpinia sappan L. Phanginin J docks with the TRPV1 molecule and may inhibit nociceptive sensory signal transduction by antagonizing TRPV1. Phanginin J can be used in research related to chemotherapy-induced peripheral neuropathy (CIPN)[1][2].
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Phanginin J | Phanginin J is a Cassane-type furanoditerpene found in the seeds of Caesalpinia sappan L. Phanginin J docks with the TRPV1 molecule and may inhibit nociceptive sensory signal transduction by antagonizing TRPV1. Phanginin J can be used in research related to chemotherapy-induced peripheral neuropathy (CIPN). | |||||||||||||||||||||
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References
- [1]. Yodsaoue O, et al. Phanginin A-K, diterpenoids from the seeds of Caesalpinia sappan Linn. Phytochemistry. 2008 Mar;69(5):1242-9.
- [2]. Aliyah AN, et al. In silico molecular docking study from Moringa oleifera and Caesalpinia sappan L. secondary metabolites as antagonist TRPV1. Journal of Medicinal and Pharmaceutical Chemistry Research. 2023;5(10):885-894.
