1015856-60-6
1015856-60-6
Chemical Structure
Flunixin-d3
Synonym(s): Sch 14714-d3
- CAS No.: 1015856-60-6
- Formula:C14H8D3F3N2O2
- Molecular Weight:299.26
IUPAC Name: 2-((2-(methyl-d3)-3-(trifluoromethyl)phenyl)amino)nicotinic acid
InChIKey: NOOCSNJCXJYGPE-FIBGUPNXSA-N
SMILES: N(C1=C(C(O)=O)C=CC=N1)C2=C(C([2H])([2H])[2H])C(C(F)(F)F)=CC=C2
Biological Activity: Flunixin-d3 is the deuterium labeled Flunixin. Flunixin Meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity[1][2].
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Flunixin-d3 | Flunixin-d3 is the deuterium labeled Flunixin. Flunixin Meglumine is a potent inhibitor of COX used as analgesic agent with anti-inflammatory and antipyretic activity. | |||||||||||||||||||||
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Flunixin | Flunixin is a cyclooxygenase (COX) inhibitor with IC50 values of 0.55 and 3.24 μM for COX-1 and COX-2, respectively. Flunixin shows anti-inflammatory effects. | |||||||||||||||||||||
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References
- [1]. Cox L, et al. Levomepromazine for nausea and vomiting in palliative care. Cochrane Database Syst Rev. 2015;2015(11):CD009420. Published 2015 Nov 2. [Content Brief]
- [2]. Cheng Z, et al. Measurement of cyclooxygenase inhibition in vivo: a study of two non-steroidal anti-inflammatory drugs in sheep. Inflammation. 1998 Aug;22(4):353-66. [Content Brief]
Keywords
