102130-90-5
102130-90-5
Chemical Structure
Isoprocurcumenol
- CAS No.: 102130-90-5
- Formula:C15H22O2
- Molecular Weight:234.33
IUPAC Name: (1S,3aR,8aS)-1-hydroxy-1-methyl-4-methylene-7-(propan-2-ylidene)octahydroazulen-6(1H)-one
InChIKey: ITIGZFMSPAFZAE-WHOFXGATSA-N
SMILES: O=C1CC([C@]2([H])CC[C@](C)(O)[C@@]2([H])C/C1=C(C)\C)=C
Biological Activity: Isoprocurcumenol is a guaiane type sesquiterpene, that can be isolated from Curcuma comosa. Isoprocurcumenol can activate EGFR signaling. Isoprocurcumenol increases the phosphorylation of ERK and AKT. Isoprocurcumenol promotes the proliferation of keratinocytes[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Isoprocurcumenol | 95.41% | Isoprocurcumenol is a guaiane type sesquiterpene, that can be isolated from Curcuma comosa. Isoprocurcumenol can activate EGFR signaling. Isoprocurcumenol increases the phosphorylation of ERK and AKT. Isoprocurcumenol promotes the proliferation of keratinocytes. | ||||||||||||||||||||
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References
- [1]. Qu Y, et al. Sesquiterpenes from Curcuma comosa. J Nat Med. 2009 Jan;63(1):102-4. [Content Brief]
- [2]. Anuchapreeda S, et al. Cytotoxicity and inhibition of leukemic cell proliferation by sesquiterpenes from rhizomes of Mah-Lueang (Curcuma cf. viridiflora Roxb.). Bioorg Med Chem Lett. 2018 Feb 1;28(3):410-414. [Content Brief]
- [3]. Kwon PK, et al. Isoprocurcumenol Supports Keratinocyte Growth and Survival through Epidermal Growth Factor Receptor Activation. Int J Mol Sci. 2021 Nov 22;22(22):12579. [Content Brief]
Keywords
