Sesquiterpenes from Curcuma comosa

  • J Nat Med. 2009 Jan;63(1):102-4. doi: 10.1007/s11418-008-0282-8.
Yang Qu  1 ,  Fengming Xu ,  Seikou Nakamura ,  Hisashi Matsuda ,  Yutana Pongpiriyadacha ,  Lijun Wu ,  Masayuki Yoshikawa
Affiliations
  • 1. School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016, China.
PMID: 18663560 DOI: 10.1007/s11418-008-0282-8
Abstract

From the dried rhizomes of Curcuma comosa cultivating in Thailand, 26 known Sesquiterpenes were isolated: zederone, zederone epoxide, furanodienone, isofuranodienone, 1(10)Z,4Z-furanodiene-6-one, glechomanolide, dehydrocurdione, neocurdione, curdione, 7 alpha-hydroxyneocurdione, 7 beta-hydroxycurdione, germacrone-1(10),4-diepoxide, germacrone, 13-hydroxygermacrone, curzerenone, curcolonol, alismol, alismoxide, zedoarondiol, isozedoarondiol, procurcumenol, isoprocurcumenol, aerugidiol, zedoalactone B, curcumenone, and curcumadione. Their structures were elucidated on the basis of physicochemical evidence. Among them, glechomanolide, curzerenone, curcolonol, alismol, alismoxide, and zedoarondiol showed no significant optical activities, so they may be artifact products during the isolation or drying process.

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