103360-00-5
Chemical Structure
YM 133
Synonym(s): IMC-XV
- CAS No.: 103360-00-5
- Formula:C55H85NO19
- Molecular Weight:1064.26
IUPAC Name: 6-((4-(dimethylamino)-6-(((11Z,13Z)-16-ethyl-4-hydroxy-15-(((5-hydroxy-3,4-dimethoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)-5,9,13-trimethyl-2,10-dioxo-7-(2-oxoethyl)oxacyclohexadeca-11,13-dien-6-yl)oxy)-5-hydroxy-2-methyltetrahydro-2H-pyran-3-yl)oxy)-4-hydroxy-2,4-dimethyltetrahydro-2H-pyran-3-yl 2-(4-methoxyphenyl)acetate
InChIKey: SHXNTUGMIOZCCG-RMPFSPEESA-N
SMILES: CN(C)C(C(C(OC1C(CC(C(/C=C\C(C)=C/C(COC2C(C(C(O)C(C)O2)OC)OC)C(CC)OC(CC(O)C1C)=O)=O)C)CC=O)OC3C)O)C3OC4CC(O)(C(OC(CC5=CC=C(OC)C=C5)=O)C(C)O4)C
Biological Activity: YM 133 (IMC-XV) is a semisynthetic macrolide antibiotic with potent bactericidal activity. YM 133 shows activity against Erythromycin (HY-B0220)-, Josamycin (HY-B1920)-, and rokitamycin-resistant (MIC ≥ 100 μg/mL) strains of staphylococci, streptococci, Bacteroides spp., and Clostridium spp. YM 133 exhibits excellent activity against macrolide-resistant strains and against anaerobes. YM 133 can be used for antibacterial research[1].
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YM 133 | YM 133 (IMC-XV) is a semisynthetic macrolide antibiotic with potent bactericidal activity. YM 133 shows activity against Erythromycin (HY-B0220)-, Josamycin (HY-B1920)-, and rokitamycin-resistant (MIC ≥ 100 μg/mL) strains of staphylococci, streptococci, Bacteroides spp., and Clostridium spp. YM 133 exhibits excellent activity against macrolide-resistant strains and against anaerobes. YM 133 can be used for antibacterial research. | |||||||||||||||||||||
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Keywords
