103884-98-6
![9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-w334680.gif "9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin Chemical Structure")
Chemical Structure
9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin
- CAS No.: 103884-98-6
- Formula:C10H12FN5O4
- Molecular Weight:285.23
IUPAC Name: 2-amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one
InChIKey: UXUZARPLRQRNNX-AYQXTPAHSA-N
SMILES: O[C@H]1[C@H](F)[C@H](N2C=NC3=C2NC(N)=NC3=O)O[C@@H]1CO
Biological Activity: 2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one (9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin | 99.45% | 2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one (9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | ||||||||||||||||||||
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