1077626-51-7
1077626-51-7
Chemical Structure
HZ52
- CAS No.: 1077626-51-7
- Formula:C24H26ClN3O2S
- Molecular Weight:456.00
IUPAC Name: 2-((4-([1,1'-biphenyl]-4-ylamino)-6-chloropyrimidin-2-yl)thio)octanoic acid
InChIKey: MLNIGXYHGQLWLD-UHFFFAOYSA-N
SMILES: ClC1=CC(NC2=CC=C(C=C2)C3=CC=CC=C3)=NC(SC(C(O)=O)CCCCCC)=N1
Biological Activity: HZ52 is a potent, reversible 5-lipoxygenase inhibitor, blocking leukotriene synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes[1].
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HZ52 | HZ52 is a potent, reversible 5-lipoxygenase inhibitor, blocking leukotriene synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes. | |||||||||||||||||||||
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References
Keywords
