1. Metabolic Enzyme/Protease
  2. Lipoxygenase
  3. HZ52

HZ52 is a potent, reversible 5-lipoxygenase inhibitor, blocking leukotriene synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes.

For research use only. We do not sell to patients.

HZ52 Chemical Structure

HZ52 Chemical Structure

CAS No. : 1077626-51-7

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Description

HZ52 is a potent, reversible 5-lipoxygenase inhibitor, blocking leukotriene synthesis with an IC50 of 0.7 μM in intact human polymorphonuclear leukocytes[1].

Molecular Weight

456.00

Formula

C24H26ClN3O2S

CAS No.
SMILES

ClC1=CC(NC2=CC=C(C=C2)C3=CC=CC=C3)=NC(SC(C(O)=O)CCCCCC)=N1

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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HZ52 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
HZ52
Cat. No.:
HY-112553
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