107827-77-0
Chemical Structure
5-Dodecanoylaminofluorescein
- CAS. Nr.: 107827-77-0
- Formula:C32H35NO6
- Molecular Weight:529.62
IUPAC Name: N-(3',6'-dihydroxy-3-oxo-3H-spiro[isobenzofuran-1,9'-xanthen]-5-yl)dodecanamide
InChIKey: VJNRUQFWKRLMSL-UHFFFAOYSA-N
SMILES: CCCCCCCCCCCC(NC1=CC2=C(C3(C4=C(OC5=C3C=CC(O)=C5)C=C(O)C=C4)OC2=O)C=C1)=O
Biological Activity: 5-Dodecanoylaminofluorescein is an amphipathic (amphoteric) fluorescent probe (Ex/Em = 485 nm/515-535 nm), which consists of a hydrophilic fluorescein core and a hydrophobic dodecanoyl group (C12 fatty acid chain) linked by an amide bond. 5-Dodecanoylaminofluorescein is mainly used as an interface-localized radical trapping/indicator probe. Dodecanoylaminofluorescein can be used for the determination of the antioxidant properties of emulsions, or can serve as a lipophilic drug model for the study of passive skin penetration when encapsulated in tyrosine-derived nanospheres[1][2][3].
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5-Dodecanoylaminofluorescein | 99.32% | 5-Dodecanoylaminofluorescein is an amphipathic (amphoteric) fluorescent probe (Ex/Em = 485 nm/515-535 nm), which consists of a hydrophilic fluorescein core and a hydrophobic dodecanoyl group (C12 fatty acid chain) linked by an amide bond. 5-Dodecanoylaminofluorescein is mainly used as an interface-localized radical trapping/indicator probe. Dodecanoylaminofluorescein can be used for the determination of the antioxidant properties of emulsions, or can serve as a lipophilic drug model for the study of passive skin penetration when encapsulated in tyrosine-derived nanospheres. | ||||||||||||||||||||
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- [1]. Thorsteinsson MV, et al. 5-Dodecanoylaminofluorescein as a probe for the determination of critical micelle concentration of detergents using fluorescence anisotropy. Anal Biochem. 2005;340(2):220-225. [Content Brief]
- [2]. Sheihet L, et al. Tyrosine-derived nanospheres for enhanced topical skin penetration. Int J Pharm. 2008;350(1-2):312-319. [Content Brief]
- [3]. Wang S, et al. Integration of (+)-catechin and β-sitosterol to achieve excellent radical-scavenging activity in emulsions. Food Chem. 2019;272:596-603. [Content Brief]
Keywords
