1110502-30-1
1110502-30-1
Chemical Structure
JAK2-IN-5
- CAS No.: 1110502-30-1
- Formula:C17H20N4O2S
- Molecular Weight:344.43
IUPAC Name: 4-(3-amino-1H-indazol-5-yl)-N-(tert-butyl)benzenesulfonamide
InChIKey: KFJCXIOVAGJCKB-UHFFFAOYSA-N
SMILES: O=S(=O)(NC(C)(C)C)C=1C=CC(=CC1)C2=CC=C3NN=C(N)C3=C2
Biological Activity: JAK2-IN-5 (Compound 13) is a selective JAK kinase inhibitor, with an IC50 of 0.078 μM against JAK-2 and an IC50 of 0.206 μM against JAK-2V617F. JAK2-IN-5 can be used for the research of myeloproliferative disorders[1].
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JAK2-IN-5 | JAK2-IN-5 (Compound 13) is a selective JAK kinase inhibitor, with an IC50 of 0.078 μM against JAK-2 and an IC50 of 0.206 μM against JAK-2V617F. JAK2-IN-5 can be used for the research of myeloproliferative disorders. | |||||||||||||||||||||
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References
Keywords
