1111460-83-3
1111460-83-3
Chemical Structure
TLR8 antagonist-1
- CAS No.: 1111460-83-3
- Formula:C21H29N3O4
- Molecular Weight:387.47
InChIKey: OMYHFYBKBHLXKI-UHFFFAOYSA-N
SMILES: CC1=NOC(C)=C1COC2=C(OC)C=C(C(NC3CCN(CC)CC3)=O)C=C2
Biological Activity: TLR8 antagonist-1 (Compound 10) is a selective TLR8 antagonist. TLR8 antagonist-1 can inhibit TLR8-mediated inflammation and signaling pathways, reduce the recruitment of MyD88, and inhibit the NF-κB and IRF pathways. TLR8 antagonist-1 has anti-inflammatory activity[1].
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TLR8 antagonist-1 | 99.95% | TLR8 antagonist-1 (Compound 10) is a selective TLR8 antagonist. TLR8 antagonist-1 can inhibit TLR8-mediated inflammation and signaling pathways, reduce the recruitment of MyD88, and inhibit the NF-κB and IRF pathways. TLR8 antagonist-1 has anti-inflammatory activity. | ||||||||||||||||||||
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References
Keywords
