1170694-29-7
1170694-29-7
Chemical Structure
RJ-34
- CAS No.: 1170694-29-7
- Formula:C22H22N2O5
- Molecular Weight:394.42
IUPAC Name: 10-(2-(dimethylamino)ethyl)-6,7-dimethoxy-[1,3]dioxolo[4',5':3,4]benzo[1,2-f]benzo[cd]indol-9(10H)-one
InChIKey: XEOKAJIDDOWYMB-UHFFFAOYSA-N
SMILES: O=C1N(CCN(C)C)C2=C3C1=CC(OC)=C(OC)C3=C(C=C4)C(C5=C4OCO5)=C2
Biological Activity: RJ-34, an aristolactam analogue, exhibits potent antitumor activities against a broad array of cancer cell lines with GI50 values in the subnanomolar range (GI50 <0.1 nM for A431, MES-SA, MES-SA/DX5, HCT-15, and HCT-15/CLO2 cells)[1].
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RJ-34 | RJ-34, an aristolactam analogue, exhibits potent antitumor activities against a broad array of cancer cell lines with GI50 values in the subnanomolar range (GI50 <0.1 nM for A431, MES-SA, MES-SA/DX5, HCT-15, and HCT-15/CLO2 cells). | |||||||||||||||||||||
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References
Keywords
