117796-52-8
Chemical Structure
N-Acetyldesloratadine
Synonym(s): SCH-37370
- CAS. Nr.: 117796-52-8
- Formula:C21H21ClN2O
- Molecular Weight:352.86
IUPAC Name: 1-(4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidin-1-yl)ethan-1-one
InChIKey: FLTBEMVEAFMWDD-UHFFFAOYSA-N
SMILES: ClC1=CC=C2C(CCC3=CC=CN=C3/C2=C4CCN(CC\4)C(C)=O)=C1
Biological Activity: N-Acetyldesloratadine (SCH-37370) is a potent, orally active dual antagonist of platelet-activating factor (PAF) and histamine. N-Acetyldesloratadine inhibits PAF-induced aggregation of human platelets, with an IC50 of 0.6 µM. N-Acetyldesloratadine can be used for the study of allergic diseases, such as asthma[1].
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N-Acetyldesloratadine | 99.93% | N-Acetyldesloratadine (SCH-37370) is a potent, orally active dual antagonist of platelet-activating factor (PAF) and histamine. N-Acetyldesloratadine inhibits PAF-induced aggregation of human platelets, with an IC50 of 0.6 µM. N-Acetyldesloratadine can be used for the study of allergic diseases, such as asthma. | ||||||||||||||||||||
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Keywords
