118006-14-7
Chemical Structure
DDN
- CAS No.: 118006-14-7
- Formula:C14H8Cl2O6
- Molecular Weight:343.12
IUPAC Name: 6,7-dichloro-5,8-dioxo-5,8-dihydronaphthalene-1,4-diyl diacetate
InChIKey: QIJKSJNUTOPANC-UHFFFAOYSA-N
SMILES: O=C1C(Cl)=C(Cl)C(C2=C1C(OC(C)=O)=CC=C2OC(C)=O)=O
Biological Activity: DDN is a selective insulin receptor (Insulin Receptor) activator, an insulin sensitizer, and a glucose-lowering insulin mimetic with oral bioavailability. DDN can directly bind to the receptor kinase domain and induce Akt and ERK phosphorylation, and it can also enhance insulin's effect on glucose uptake. DDN significantly reduces blood glucose levels in wild-type and diabetic ob/ob and db/db mice[1].
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DDN | DDN is a selective insulin receptor (Insulin Receptor) activator, an insulin sensitizer, and a glucose-lowering insulin mimetic with oral bioavailability. DDN can directly bind to the receptor kinase domain and induce Akt and ERK phosphorylation, and it can also enhance insulin's effect on glucose uptake. DDN significantly reduces blood glucose levels in wild-type and diabetic ob/ob and db/db mice. | |||||||||||||||||||||
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Keywords
