1185242-69-6
Chemical Structure
MTIC-d3
- CAS No.: 1185242-69-6
- Formula:C5H5D3N6O
- Molecular Weight:171.18
IUPAC Name: (E)-4-(3-(methyl-d3)triaz-1-en-1-yl)-1H-imidazole-5-carboxamide
InChIKey: MVBPAIHFZZKRGD-FIBGUPNXSA-N
SMILES: NC(C1=C(N=CN1)/N=N/NC([2H])([2H])[2H])=O
Biological Activity: MTIC-d3 is deuterium labeled MTIC. MTIC is the active metabolite of Temozolomide (TMZ). MITC has lower bioavailability in the brain compared with TMZ, because the agent’s permeability through biological barriers and tumor cell membranes affects bioavailability. MITC exhibits low affinity to biological membrane[1].
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MTIC-d3 | MTIC-d3 is deuterium labeled MTIC. MTIC is the active metabolite of Temozolomide (TMZ). MITC has lower bioavailability in the brain compared with TMZ, because the agent’s permeability through biological barriers and tumor cell membranes affects bioavailability. MITC exhibits low affinity to biological membrane. | |||||||||||||||||||||
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MTIC (Standard) | ≥98% | MTIC (Standard) is the analytical standard of MTIC. This product is intended for research and analytical applications. MTIC, the active metabolite of Temozolomide (TMZ), is a DNA alkylating agent. MTIC has antitumor activity . | ||||||||||||||||||||
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MTIC-13C | MTIC-13C is the 13C-labeled MTIC (HY-119696). MTIC, the active metabolite of Temozolomide (TMZ), is a DNA alkylating agent. MTIC has antitumor activity | |||||||||||||||||||||
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MTIC | 98.83% | MTIC, the active metabolite of Temozolomide (TMZ), is a DNA alkylating agent. MTIC has antitumor activity . | ||||||||||||||||||||
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Keywords
