1194235-46-5
Chemical Structure
YSY01A
- CAS No.: 1194235-46-5
- Formula:C29H38BN5O5
- Molecular Weight:547.45
InChIKey: BJJCLDNVNAULGO-GNKBHMEESA-N
SMILES: O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=C(C=CC=C2)C2=C1)C(N[C@H](B(O)O)CC(C)C)=O)=O)C3=CN=CC=N3
Biological Activity: YSY01A is a proteasome inhibitor that can suppress cancer cell survival by inducing apoptosis (Apoptosis). Its IC50 values are 51.0 nM for HEK293T, 9.2 nM for A549, 5.2 nM for MCF-7, 8.9 nM for MGC-803, and 35.4 nM for PC-3M cells. Additionally, YSY01A eliminates constitutive STAT3 signaling by downregulating gp130 and JAK2 in human A549 lung cancer cells. YSY01A holds promise for research in the field of cancer therapy[1].
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YSY01A | YSY01A is a proteasome inhibitor that can suppress cancer cell survival by inducing apoptosis (Apoptosis). Its IC50 values are 51.0 nM for HEK293T, 9.2 nM for A549, 5.2 nM for MCF-7, 8.9 nM for MGC-803, and 35.4 nM for PC-3M cells. Additionally, YSY01A eliminates constitutive STAT3 signaling by downregulating gp130 and JAK2 in human A549 lung cancer cells. YSY01A holds promise for research in the field of cancer therapy. | |||||||||||||||||||||
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Keywords
