1198784-83-6
Chemical Structure
Glucocorticoid receptor/IL-6-IN-2
- CAS No.: 1198784-83-6
- Formula:C22H23ClF3N3O4S
- Molecular Weight:517.95
InChIKey: UAYXTLWPZTYJEV-UHFFFAOYSA-N
SMILES: O=C(C1=CC(Cl)=CC=C1C(C)(CC(CC2=CC3=C(N2)C=NC(S(=O)(C)=O)=C3)(C(F)(F)F)O)C)N
Biological Activity: Glucocorticoid receptor/IL-6-IN-2 (Compound 36) is a selective dual inhibitor targeting the glucocorticoid receptor (GR) and IL-6 signaling pathway (IC50 values of 40 nM and 19 nM, respectively). Glucocorticoid receptor/IL-6-IN-2 is promising for research of inflammatory diseases like rheumatoid arthritis and asthma[1].
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Glucocorticoid receptor/IL-6-IN-2 | Glucocorticoid receptor/IL-6-IN-2 (Compound 36) is a selective dual inhibitor targeting the glucocorticoid receptor (GR) and IL-6 signaling pathway (IC50 values of 40 nM and 19 nM, respectively). Glucocorticoid receptor/IL-6-IN-2 is promising for research of inflammatory diseases like rheumatoid arthritis and asthma. | |||||||||||||||||||||
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Keywords