1207197-70-3
Chemical Structure
GSK1331268
- CAS No.: 1207197-70-3
- Formula:C17H19ClN6
- Molecular Weight:342.83
IUPAC Name: 2-((4-(5-chloropyrimidin-2-yl)piperazin-1-yl)methyl)-1-methyl-1H-benzo[d]imidazole
InChIKey: IXXZGBOSQDVMTC-UHFFFAOYSA-N
SMILES: ClC1=CN=C(N2CCN(CC2)CC3=NC4=C(N3C)C=CC=C4)N=C1
Biological Activity: GSK1331268 is a selective, orally active agonist for mGluR2 with a pEC50 of 6.9. GSK1331268 exhibits good blood-brain barrier penetration. GSK1331268 regulates glutamate signaling, and can be used in research of neurodegenerative and neuropsychiatric diseases[1].
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GSK1331268 | GSK1331268 is a selective, orally active agonist for mGluR2 with a pEC50 of 6.9. GSK1331268 exhibits good blood-brain barrier penetration. GSK1331268 regulates glutamate signaling, and can be used in research of neurodegenerative and neuropsychiatric diseases. | |||||||||||||||||||||
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Keywords