1212704-51-2
1212704-51-2
Chemical Structure
Jarin-1
- CAS No.: 1212704-51-2
- Formula:C28H29N3O4
- Molecular Weight:471.55
IUPAC Name: N-((1R,5S)-3-(3-methoxypropanoyl)-8-oxo-1,3,4,5,6,8-hexahydro-2H-1,5-methanopyrido[1,2-a][1,5]diazocin-9-yl)-[1,1'-biphenyl]-4-carboxamide
InChIKey: LMVUVKIGGHXSJX-WMZHIEFXSA-N
SMILES: O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC(C3=O)=CC=C4N3C[C@]5([H])CN(C(CCOC)=O)C[C@@]4([H])C5
Biological Activity: Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor with an IC50 of 3.8 μM. Jarin-1 specific inhibits bioactive JA (jasmonoyl-isoleucine, JA-Ile) biosynthesis in Arabidopsis and other plants[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Jarin-1 | 99.17% | Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor with an IC50 of 3.8 μM. Jarin-1 specific inhibits bioactive JA (jasmonoyl-isoleucine, JA-Ile) biosynthesis in Arabidopsis and other plants. | ||||||||||||||||||||
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References
- [1]. Delgado LD, et al. Application of a JA-Ile Biosynthesis Inhibitor to Methyl Jasmonate-Treated Strawberry Fruit Induces Upregulation of Specific MBW Complex-Related Genes and Accumulation of Proanthocyanidins. Molecules. 2018 Jun 13;23(6). pii: E1433. [Content Brief]
- [2]. Meesters C, et al. A chemical inhibitor of jasmonate signaling targets JAR1 in Arabidopsis thaliana. Nat Chem Biol. 2014 Oct;10(10):830-6. [Content Brief]
Keywords
