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Jarin-1 

Cat. No.: HY-115521 Purity: >98.0%
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Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor with an IC50 of 3.8 μM. Jarin-1 specific inhibits bioactive JA (jasmonoyl-isoleucine, JA-Ile) biosynthesis in Arabidopsis and other plants.

For research use only. We do not sell to patients.

Jarin-1 Chemical Structure

Jarin-1 Chemical Structure

CAS No. : 1212704-51-2

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1 mg USD 200 In-stock
Estimated Time of Arrival: December 31
5 mg USD 600 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Jarin-1 is a jasmonic acid-amido synthetase (JAR1) inhibitor with an IC50 of 3.8 μM. Jarin-1 specific inhibits bioactive JA (jasmonoyl-isoleucine, JA-Ile) biosynthesis in Arabidopsis and other plants[1][2].

IC50 & Target

Jasmonic acid-amido synthetase (JAR1)[1][2]

In Vitro

A higher redness of strawberry fruit skin and anthocyanin content in MeJA-treated fruits with respect to Jarin-1-treated ones concomitant with an upregulation of FaANS and FaUFGT genes is found. Inversely, the proanthocyanidin (PA) content was higher in Jarin-1- and MeJA + Jarin-1-treated than in MeJA-treated fruits. MeJA + Jarin-1 treatment resulted in an upregulation of FaANR and associated transcription factors such as FabHLH33 and FaMYB9/11 along with FaJMT and FaJAR1.2. JA-responsive elements in the promoter regions of FaMYB1/9/10/11 genes is found. PA biosynthesis-related genes can be upregulated by the application of Jarin-1 to MeJA-treated fruit, thus increasing PA accumulation in strawberry[1].

Molecular Weight

471.55

Formula

C₂₈H₂₉N₃O₄

CAS No.

1212704-51-2

SMILES

O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC(C3=O)=CC=C4N3C[[email protected]]5([H])CN(C(CCOC)=O)C[[email protected]@]4([H])C5

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >98.0%

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Keywords:

Jarin-1Jarin1Jarin 1OthersAnthocyaninJAR1methyljasmonateFaANSFaUFGTjasmonicacidMeJAbiosynthesisInhibitorinhibitorinhibit

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Jarin-1
Cat. No.:
HY-115521
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