1215703-04-0
Chemical Structure
BMS 182874 hydrochloride
- CAS No.: 1215703-04-0
- Formula:C17H20ClN3O3S
- Molecular Weight:381.88
IUPAC Name: 5-(dimethylamino)-N-(3,4-dimethylisoxazol-5-yl)naphthalene-1-sulfonamide hydrochloride
InChIKey: UZZFRNZGYDOBAO-UHFFFAOYSA-N
SMILES: O=S(C1=C2C=CC=C(C2=CC=C1)N(C)C)(NC3=C(C(C)=NO3)C)=O.Cl
Biological Activity: BMS 182874 hydrochloride is an orallyactive, highly selective endothelin receptor (ETA receptor) antagonist, with IC50 value of 0.150 μM, Ki of 0.055 μM. BMS 182874 hydrochloride reduces the arterial pressure of Deoxycorticosterone acetate (HY-B1472) induced hypertension model in rats, and can be used for cardiovascular disease research[1].
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BMS 182874 hydrochloride | BMS 182874 hydrochloride is an orallyactive, highly selective endothelin receptor (ETA receptor) antagonist, with IC50 value of 0.150 μM, Ki of 0.055 μM. BMS 182874 hydrochloride reduces the arterial pressure of Deoxycorticosterone acetate (HY-B1472) induced hypertension model in rats, and can be used for cardiovascular disease research. | |||||||||||||||||||||
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Keywords
