1217661-14-7
Chemical Structure
Voriconazole-d3
Synonym(s): UK-109496-d3
- CAS No.: 1217661-14-7
- Formula:C16H11D3F3N5O
- Molecular Weight:352.33
IUPAC Name: (2R,3S)-2-(2,4-difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1H-1,2,4-triazol-1-yl)butan-4,4,4-d3-2-ol
InChIKey: BCEHBSKCWLPMDN-QLWAGJNOSA-N
SMILES: [2H]C([2H])([2H])[C@@H](C1=NC=NC=C1F)[C@@](O)(C2=C(C=C(C=C2)F)F)CN3C=NC=N3
Biological Activity: Voriconazole-d3 is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes[1][2].
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Voriconazole-d3 | 99.90% | Voriconazole-d3 is the deuterium labeled Voriconazole. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes. | ||||||||||||||||||||
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Voriconazole (Standard) | 99.90% | Voriconazole (Standard) is the analytical standard of Voriconazole. This product is intended for research and analytical applications. Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes. | ||||||||||||||||||||
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(±)-Voriconazole-d3 | (±)-Voriconazole-d3 is the deuterium labeled (±)-Voriconazole. | |||||||||||||||||||||
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Voriconazole | 99.45% | Voriconazole (UK-109496) is a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. Voriconazole exerts its antifungal activity by inhibition of 14-α-lanosterol demethylation, which is mediated by fungal cytochrome P450 enzymes. Voriconazole can penetrate the blood brain barrier (BBB). | ||||||||||||||||||||
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