1219803-62-9
Chemical Structure
Octopamine-d4 hydrochloride
Synonym(s): (±)-p-Octopamine-d4 hydrochloride
- CAS No.: 1219803-62-9
- Formula:C8H9D3ClNO2
- Molecular Weight:192.66
IUPAC Name: 4-(2-amino-1-hydroxyethyl-1,2,2-d3)phenol hydrochloride
InChIKey: PUMZXCBVHLCWQG-IJJJTAPTSA-N
SMILES: NC([2H])([2H])C(C1=CC=C(C=C1)O)([2H])O.[H]Cl
Biological Activity: Octopamine-d4 (hydrochloride) is the deuterium labeled Octopamine hydrochloride. Octopamine ((±)-p-Octopamine) hydrochloride, a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine hydrochloride can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine hydrochloride increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure[1][2][3].
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Octopamine-d4 hydrochloride | 98.0% | Octopamine-d4 (hydrochloride) is the deuterium labeled Octopamine hydrochloride. Octopamine ((±)-p-Octopamine) hydrochloride, a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine hydrochloride can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine hydrochloride increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure. | ||||||||||||||||||||
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References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Farooqui T. Octopamine-mediated neuromodulation of insect senses. Neurochem Res. 2007;32(9):1511-1529. [Content Brief]
- [3]. Roeder T. Octopamine in invertebrates. Prog Neurobiol. 1999;59(5):533-561. [Content Brief]
