122021-74-3
Chemical Structure
Magnesium Lithospermate B
- CAS No.: 122021-74-3
- Formula:C36H28MgO16
- Molecular Weight:740.90
InChIKey: ANUBYMNVOPVATP-RBRJVDKYSA-L
SMILES: O=C1[O-][Mg+2]23O=C(/C=C\C4=C5[C@H](C(O[C@H](CC6=CC=C(C(O)=C6)O)C([O-]3)=O)=O2)[C@@H](C7=CC=C(C(O)=C7)O)OC5=C(O)C=C4)O[C@@H]1CC8=CC=C(C(O)=C8)O
Biological Activity: Magnesium Lithospermate B, is a derivative of caffeic acid tetramer and an inhibitor of Na+/K+ ATPase, which can be extracted from Salviae miltiorrhizae. Magnesium Lithospermate B is widely used for the research of cardiovascular diseases, and it can protect against glucose-induced intracellular oxidative damage. Magnesium Lithospermate B also suppresses neuroin?ammation and attenuates neurodegeneration[1][2][3].
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Magnesium Lithospermate B | 99.45% | Magnesium Lithospermate B, is a derivative of caffeic acid tetramer and an inhibitor of Na+/K+ ATPase, which can be extracted from Salviae miltiorrhizae. Magnesium Lithospermate B is widely used for the research of cardiovascular diseases, and it can protect against glucose-induced intracellular oxidative damage. Magnesium Lithospermate B also suppresses neuroin?ammation and attenuates neurodegeneration. | ||||||||||||||||||||
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- [1]. Magnesium lithospermate B possesses inhibitory activity on Na+,K+‐ATPase and neuroprotective effects against ischemic stroke
- [2]. Park CH, et, al. Magnesium Lithospermate B from Salvia miltiorrhiza Bunge Ameliorates Aging-Induced Renal Inflammation and Senescence via NADPH Oxidase-Mediated Reactive Oxygen Generation. Phytother Res. 2017 May;31(5):721-728. [Content Brief]
- [3]. Quan W, et, al. Antioxidant properties of magnesium lithospermate B contribute to the cardioprotection against myocardial ischemia/reperfusion injury in vivo and in vitro. J Tradit Chin Med. 2013 Feb; 33(1): 85-91. [Content Brief]
Keywords
