1223002-54-7
1223002-54-7
Chemical Structure
QL-IX-55
- CAS No.: 1223002-54-7
- Formula:C24H14F4N4O
- Molecular Weight:450.39
IUPAC Name: 9-(6-aminopyridin-3-yl)-1-(4-fluoro-3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one
InChIKey: MXRMEHBVJBSIPI-UHFFFAOYSA-N
SMILES: NC1=NC=C(C2=CC=C(N=CC(C=C3)=C4N(C5=CC(C(F)(F)F)=C(F)C=C5)C3=O)C4=C2)C=C1
Biological Activity: QL-IX-55 is a selective ATP-competitive inhibitor of mTORC1/2 with IC50s of 50/50/10-50 nM for Human mTORC1/Yeast mTORC1/Yeast mTORC2, respectively.
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QL-IX-55 | QL-IX-55 is a selective ATP-competitive inhibitor of mTORC1/2 with IC50s of 50/50/10-50 nM for Human mTORC1/Yeast mTORC1/Yeast mTORC2, respectively. | |||||||||||||||||||||
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Keywords
