1253291-12-1

GRN-529 Chemical Structure
1253291-12-1

Chemical Structure

GRN-529

  • CAS No.: 1253291-12-1
  • Formula:C22H15F2N3O2
  • Molecular Weight:391.37

IUPAC Name: (4-(difluoromethoxy)-3-(pyridin-2-ylethynyl)phenyl)(5,7-dihydro-6H-pyrrolo[3,4-b]pyridin-6-yl)methanone

InChIKey: JITMSIRHBAVREW-UHFFFAOYSA-N

SMILES: O=C(N1CC2=NC=CC=C2C1)C3=CC=C(C(C#CC4=NC=CC=C4)=C3)OC(F)F

Biological Activity: GRN-529 is a negative allosteric modulator (NAM) for mGluR5. GRN-259 modulates sleep-wake activity, and exhibits anxiolytic efficacy in rats[1].

Cat. No. Product Name Purity Description Pricing
HY-124393 		GRN-529 GRN-529 is a negative allosteric modulator (NAM) for mGluR5. GRN-259 modulates sleep-wake activity, and exhibits anxiolytic efficacy in rats.
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