1262395-13-0
Chemical Structure
NMS-P515
- CAS No.: 1262395-13-0
- Formula:C21H29N3O2
- Molecular Weight:355.47
IUPAC Name: (S)-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxoisoindoline-4-carboxamide
InChIKey: OYGLTKXMFGWXJT-AWEZNQCLSA-N
SMILES: O=C(N)C1=C2C([C@H](C)N(C3CCN(C4CCCCC4)CC3)C2=O)=CC=C1
Biological Activity: NMS-P515 is a potent, orally active and stereospecific PARP-1 inhibitor, with a Kd of 16 nM and an IC50 of 27 nM (in Hela cells). Anti-tumor activity[1].
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NMS-P515 | 98.18% | NMS-P515 is a potent, orally active and stereospecific PARP-1 inhibitor, with a Kd of 16 nM and an IC50 of 27 nM (in Hela cells). Anti-tumor activity. | ||||||||||||||||||||
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Keywords